SKU: 81431986833

TMG Pro Tablets - 1000 mg, 120 tablets

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Description

TMG Pro Tablets - 1000 mg, 120 tabletsA methyl donor that complements NMN and supports heart health and liver detoxification. Supports liver detoxification Supports cardiovascular health Promotes healthy homocysteine levels Supports cellular health View Certificate of Analysis Research Supported Benefits: Supports Cellular Health. TMG is an amino acid that supports the body's methylation processes. Methylation is essential for numerous important cellular functions, including cell

A methyl donor that complements NMN and supports heart health and liver detoxification.

  • Supports liver detoxification 
  • Supports cardiovascular health 
  • Promotes healthy homocysteine levels 
  • Supports cellular health 

View Certificate of Analysis

Research-Supported Benefits:

Supports Cellular Health. TMG is an amino acid that supports the body's methylation processes. Methylation is essential for numerous important cellular functions, including cell division, energy production and producing antioxidants to fight oxidative stress.1

Supports Detoxification. The donation of methyl groups by TMG is critical for healthy liver function and detoxification.1

Supports Cardiovascular Health. TMG may decrease blood levels of homocysteine, an amino acid that is linked to poor heart health and blood vessel damage when elevated.2

References:

1. Arumugam MK, Paal MC, Donohue TM Jr, Ganesan M, Osna NA, Kharbanda KK. Beneficial Effects of Betaine: A Comprehensive Review. Biology (Basel). 2021;10(6):456. Published 2021 May 22. doi:10.3390/biology10060456 

2. McRae MP. Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis. J Chiropr Med. 2013;12(1):20-25. doi:10.1016/j.jcm.2012.11.001 doi:10.1016/j.jcm.2012.11.001 

  • Trimethylglycine (TMG), also known as betaine anhydrous, is an amino acid that supports the body's methylation processes. 
  • Methylation is a fundamental biochemical process in which one carbon atom and three hydrogen atoms (CH3) are transferred from one molecule to another. 
  • Methylation is responsible for numerous important bodily functions, such as cell division, cellular energy production, clearing histamine, metabolism, DNA expression (epigenetics), forming neurotransmitters and producing free radical-scavenging antioxidants. 
  • Our bodies contain a “methyl pool” of CH3 that is available whenever needed. As long as we have enough methyl groups stored in the pool, methylation typically is not a problem. However, there are a couple of things that may contribute to the depletion of the body's methyl pool. 
  • MTHFR Variants - Methylenetetrahydrofolate reductase (MTHFR) is a gene with common mutations that can interfere with the methylation process, causing high levels of homocysteine (a known risk factor in heart health conditions) in the blood and low folate levels. Up to 40% of the population may have one or both genetic mutations. 
  • Aging and Epigenetics - Methylation of DNA plays a crucial role in epigenetics, switching different sequences of your genetic material on and off as needed. The body's methylation ability and subsequent DNA expression are known to decline with age. Anti-aging researchers think these changes in DNA expression may be a contributing factor to many age-related diseases. 
  • NMN Supplementation and Methylation Support. When taken as a supplement, NMN may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity. Although there is currently no evidence suggesting NMN’s natural methylation process depletes the methyl pool, many top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake. 
Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 120
Amount Per Serving %DV
Trimethylglycine (TMG) (Betaine Anhydrous) 1 g (1000 mg)
† Daily Value (DV) not established
REV.10.23
  • OTHER INGREDIENTS: Cellulose, stearic acid (vegetable source), croscarmellose sodium, magnesium stearate (vegetable source).
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Take 1-6 tablets daily, divided into 2 doses, or as recommended by your healthcare professional.
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • NOTE: Keep the bottle tightly closed at all times in between usage. Keep the freshness packet in bottle. This product is very sensitive to moisture/humidity which may affect product stability. Store in a cool dry place after opening. KEEP OUT OF REACH OF CHILDREN

Tablet Form. The tablet form of TMG Pro makes it easy to take.

Higher Dose. ProHealth’s TMG Pro contains 1,000 mg of TMG as Betaine Anhydrous, whereas other TMG supplements may contain just 750 mg.

Free of Unwanted Ingredients. TMG Pro doesn’t contain yeast, wheat, gluten, sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, soy, corn, dye or preservatives.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in USA laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Shipping Notes
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SKU: 81431986833

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4.7 ★★★★★
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Lindsay Marie Cirrincione
Bozeman, US
★★★★★ 5
Incredibly durable
Size: For Medium Dog, Color: Grassgreen, Size: For Medium Dog, Color: Grassgreen
I bought this for my malinois mix when i got her last august. She's 10 months old and plays with this toy every day. This is such a durable toy! I strongly suggest this for everyone
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Reviewed in the United States on May 3, 2026
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Lauren
San Leandro, US
★★★★★ 4
He loves it! It will probably be destroyed soon though...
Size: For Medium Dog, Color: Green, Size: For Medium Dog, Color: Green
Update! This toy has definitely withstood my boy's daily chewing! It's lost some pieces for sure, but overall it's holding up and I'm very happy about it. The only downside is the squeaker is rather difficult to get to make noise. Will still definitely invest in another when this one finally goes. Original review: I bought this for my handsome pitbull/boxer mix -- the boy loves to chew toys up! He's an aggressive chewer and he was bored with the current toys we had. This toy is advertised for chewers, and I imagine if my boy wasn't such a great chewer, it would be amazing! We've had it three days now and he's already gotten a few big chunks off of it. It is definitely entertaining him though! He loves it and he seems like he's chewed himself into a daze. There is a squeaker in the bottom that seems difficult for him to get to so it doesn't squeak often -- when it does though he freaks and it's hilarious. Overall I'm very happy with this purchase. My boy is a very aggressive chewer and I know pretty much anything we get him will be destroyed soon after he gets it. With how much he is enjoying this toy, I will be buying it again for him.
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Reviewed in the United States on November 18, 2023
B
Verified Purchase
Beach Life
Cuba, US
★★★★★ 5
Outstanding Chew Toy
Size: For Large Dog, Color: Green
My dog is beyond an aggressive chewer. Toys are in pieces in minutes no matter what the manufacturer says. The squeaker? Forget it gone immediately. She has had this toy for two days and not only is it intact but she hasn’t been able to remove the squeaker!! Great product!!!
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Reviewed in the United States on March 27, 2026
C
Verified Purchase
CATHERINE A WOLF
New York, US
★★★★★ 3
Be careful. Prices come off
Size: For Medium Dog, Color: Grassgreen
My dog loves it but it does come apart. He’s not a dog that destroys things but he bit prices off of it.
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Reviewed in the United States on February 13, 2026
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Kailyn
Port Orchard, US
★★★★★ 5
Heavy duty
Size: For Medium Dog, Color: Green, Size: For Medium Dog, Color: Green
I just unboxed this so I will update if my opinion changes. I bought the medium dog toy, it’s a a great size, perfect for my 110 pound lab and my 60 pound pit terrier mix. It’s heavy duty so I don’t see this being torn apart anytime soon, it has a slight mint scent (mostly rubber). As of right now, I can confidently say that I see myself buying more from this brand. Hopefully it helps with their stinky breath, if not then at least it’s a fun toy for the pups. Update: after over a month of play I can say it’s still going pretty strong. My dog did manage to damage it a bit but if you have dogs who are rough on their toys, this is a good option. I was also surprised to find out that there is a squeaker in the base of it, the pups have to bite really hard in order to hear it, heavy duty toy. I will say one of the only downsides is that it doesn’t seem too appealing to my pups. If there are other toys around they’ll go for the other toys but occasionally will pick this. I still recommend it. Has been lasting us awhile (I have 3 pups).
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Reviewed in the United States on April 17, 2025

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