Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 25 - Jul 30
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
GLS1 Recombinant Rabbit mAb (S-2355-20)Product Specification Host Rabbit Antigen GLS1 Synonyms Glutaminase kidney isoform, mitochondrial; K glutaminase; L glutamine amidohydrolase; KIAA0838; GLS Immunogen Synthetic Peptide Location Cytoplasm, Mitochondrion Accession O94925 Clone Number S 2355 20 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu Positive Sample HeLa, 293T, A549 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | GLS1 |
| Synonyms | Glutaminase kidney isoform, mitochondrial; K-glutaminase; L-glutamine amidohydrolase; KIAA0838; GLS |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Mitochondrion |
| Accession | O94925 |
| Clone Number | S-2355-20 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Positive Sample | HeLa, 293T, A549 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu |
| IHC-P | 1:200 | Hu |
| ICC | 1:500 | Hu |
Background
GLS1, or glutaminase 1, is a mitochondrial enzyme that catalyzes the conversion of glutamine to glutamate and ammonia. It plays a crucial role in various physiological and pathological processes. In the central nervous system, GLS1 is essential for synaptic transmission and neurogenesis, as it provides the key excitatory neurotransmitter glutamate. In cancer, GLS1 is often upregulated and promotes tumor cell proliferation, survival, and metastasis by fueling the tricarboxylic acid (TCA) cycle. Additionally, in endothelial cells, GLS1 supports cell proliferation and migration through the regulation of cell cycle progression and reactive oxygen species production.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy